Abstract

Objective: Obesity is one of the modifiable risk factors of type 2 diabetes mellitus. Adiposity causes insulin resistance and diabetes by various mechanisms. This study was undertaken to determine diabetogenic effect of adiposity in relation to age for identification of vulnerable age groups.

Methods: This prospective study included 370 healthy adult non-diabetic individuals. Height and weight were recorded to calculate body mass index (BMI). Fasting blood sugar (FBS) was estimated by glucose oxidase method. 

Results: A stepwise increase in magnitude of BMI was observed with increase of age in decades. Although increase in mean FBS was observed with age, statistically significant (p = 0.00093) increase in mean FBS was observed only in 4th decade of life. Positive correlation was observed (Pearson’s correlation coefficient r = + 0.26) between BMI and FBS. 

Conclusion: With increasing age, BMI and FBS increase, especially during 4th decade of life. This emphasizes the need to target the vulnerable age group (30-40 years) for creating awareness about maintenance of ideal body weight to prevent early onset of type 2 diabetes. Positive correlation between BMI and FBS reiterates diabetogenic effect of adipose tissue and emphasizes importance of maintenance of normal BMI.

Key words: Obesity; Adiposity; Body Mass Index; Blood glucose  
 
 
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Volume 12, issue 2, April-June 2020

 


 

The worldwide spread of COVID-19 as an emerging, rapidly evolving situation, and the dramatic need of urgent medicine or vaccine, has rapidly brought new hypotheses for pathophysiology and potential medicinal agents to the fore. It is crucial that the research community provide a way to publish this research in a timely manner.

To contribute to this important public health discussion, the Electronic Physician Journal is excited to announce a fast-track procedure to help researchers publish their articles on COVID-19 related subjects that fall under the broad definition of public health, internal medicine, and pharmacology. We are especially welcome to all hypotheses about the pathological basis of the COVID-19 infection and the possible characteristics of potential medicine and vaccine. Submit your manuscript here


 

The 6th World Conference on Research Integrity (WCRI) is to be held on June 2-5, 2019 in Hong Kong.

The WCRI is the largest and most significant international conference on research integrity. Since the first conference in Lisbon in 2007, it has given researchers, teachers, funding agencies, government officials, journal editors, senior administrators, and research students opportunities to share experiences and to discuss and promote integrity in research. Read more:


 

TDR Clinical Research and Development Fellowships

Call for applications

Deadline for submission: 7 March 2019, 16:00 (GMT)

TDR provides fellowships for early- to mid-career researchers and clinical trial staff (e.g. clinicians, pharmacists, medical statisticians, data managers, other health researchers) in low- and middle-income countries (LMICs) to learn how to conduct clinical trials. Read more:


Meta-Analysis Workshops in New York, USA, and London, UK, in April and May 2019

Don't miss this exceptional opportunity to learn how to perform and report a Meta-analysis correctly. Two Meta-analysis workshops are organized in April and May 2019 by Dr. Michael Borenstein in New York, USA (April 08-10, 2019) and London, UK (May 27-29).

About the Instructor

Dr. Michael Borenstein, one of the authors of Introduction to Meta-Analysis, is widely recognized for his ability to make statistical concepts accessible to researchers as well as to statisticians. He has lectured widely on meta-analysis, including at the NIH, CDC, and FDA. Read more: