Introduction: Adenocarcinoma of the third part of the duodenum is a rare type of tumor that has challenges in its diagnosis and management. Segmental resection with pancreatic sparing is a safe and accepted choice for the surgical intervention of this type of cancer.
Case Presentation: A 33-year-old male presented with a 3-week history of symptoms of gastric outlet obstruction with anemia and weight loss. Upon investigating the patient with computed tomography and esophagogastroduodenoscopy, he was found to have an adenocarcinoma that involved the third part of the duodenum. The patient underwent segmental resection of the third and fourth part of the duodenum with pancreatic sparing. He had a smooth postoperative course. The pathological evaluation shows a 3 cm moderately differentiated adenocarcinoma with free margins. Six out of thirteen lymph nodes were having metastasis. The patient developed a soft tissue recurrence 18 months after the operation.
Take-away Lessons: Adenocarcinoma of the third part of the duodenum should be kept in mind in any patient presented with symptoms of gastric outlet obstruction. It can be managed safely with segmental resection avoiding the morbidity of resection of the pancreas.
Keywords: Adenocarcinoma of the small bowel, third part of the duodenum, segmental resection


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October-December 2019 (Volume 11, Issue 4)


The 6th World Conference on Research Integrity (WCRI) is to be held on June 2-5, 2019 in Hong Kong.

The WCRI is the largest and most significant international conference on research integrity. Since the first conference in Lisbon in 2007, it has given researchers, teachers, funding agencies, government officials, journal editors, senior administrators, and research students opportunities to share experiences and to discuss and promote integrity in research. Read more:


TDR Clinical Research and Development Fellowships

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Deadline for submission: 7 March 2019, 16:00 (GMT)

TDR provides fellowships for early- to mid-career researchers and clinical trial staff (e.g. clinicians, pharmacists, medical statisticians, data managers, other health researchers) in low- and middle-income countries (LMICs) to learn how to conduct clinical trials. Read more:

Meta-Analysis Workshops in New York, USA, and London, UK, in April and May 2019

Don't miss this exceptional opportunity to learn how to perform and report a Meta-analysis correctly. Two Meta-analysis workshops are organized in April and May 2019 by Dr. Michael Borenstein in New York, USA (April 08-10, 2019) and London, UK (May 27-29).

About the Instructor

Dr. Michael Borenstein, one of the authors of Introduction to Meta-Analysis, is widely recognized for his ability to make statistical concepts accessible to researchers as well as to statisticians. He has lectured widely on meta-analysis, including at the NIH, CDC, and FDA. Read more: